Dr Thein is Chief of the Sickle Cell Branch, NHLBI/NIH since March 2015. Prior to this, she was a professor of molecular hematology and consultant hematologist at King’s College London (KCL), where she served as clinical director of the Red Cell Centre in King’s College Hospital. At the hospital, she was involved in the care of 800 adult patients with sickle cell disease and other red blood cell disorders. She has participated and directed a wide range of clinical and translational haematology research on inherited anemias, in particular, beta hemoglobin disorders. Her research currently focuses on sickle cell disease: to better understand how a simple mutation in a single gene can cause damage in multiple organs and the extreme variability in sickle cell disease severity, and to accelerate the translation of basic discovery to therapeutic application and management.
Dr Thein is an author or co-author of more than 300 peer-reviewed research publications, invited review articles, and book chapters.